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| c. 350 BC |
| | Private financiers in Athens give loans, take deposits, change money from one currency to another and arrange credit for travellers | |
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| 299 BC |
| | Seleucus founds Antioch as a Greek city on the trade route between Mesopotamia and Europe | |
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| c. 200 BC |
| | The oasis city of Palmyra acquires importance on the caravan route between Mesopotamia and the Mediterranean | |
| | Palmyra Fotofile CG
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| 106 BC |
| | A caravan leaves China with goods destined for Persia - proof that the eastern half of the Silk Road is now open | |
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| 64 BC |
| | The Roman annexation of Syria brings the Silk Road all the way to the Mediterranean | |
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| c. 10 BC |
| | The period of stability achieved during the reign of Augustus Caesar has been given the name Pax Romana ('Roman peace') | |
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| c. 100 |
| | Theravada Buddhism, strong in south India and Sri Lanka, travels with traders through southeast Asia | |
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| c. 100 |
| | Buddhism, arriving with trade along the Silk Road from India, puts down firm roots in China | |
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| c. 150 |
| | London develops as a prosperous trading centre, at the hub of the network of Roman roads in Britain | |
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| c. 700 |
| | The quipu is used in the Wari culture and becomes the standard recording device of the Andean civilizations | |
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